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Credit: https://www.lifespan.io/news/blueberry-extract-reduces-aging-biomarkers-in-rat-livers/

Can blueberry extract reduce aging biomarkers?

July 25, 2022

Published in Oxidative Medicine and Cellular Longevity, a recent study has shown that blueberry extract can improve age-related biomarkers in livers of aging male rats. Researchers point out that blueberries are rich in anthocyanins, which have been reportedly shown to have positive effects in past studies. Additionally, they note that there hasn’t been a study done on the effect of blueberry extract on the liver as a thorough analysis. In this study, the researchers administered a refined blueberry extract at 200 milligrams per kilogram of bodyweight. The young rats were 6 months old and the aging rats were 24 months old. After the blueberry extract was given over a four week time period, the rats were euthanized and examined. The experiment had shown that the rats given blueberry extract had lost a small amount of weight compared to those in the control group who had gained weight while they aged. There are two common types of enzymes found in the liver, alanine transaminase (ALT), and aspartate transaminase (AST), and by the end of this study, both enzymes had shown a significant decrease in the group of mice who received the blueberry extract. It is normal to see an increase in levels of insulin, cholesterol, and triglycerides in rats as they age. This study showed that these levels, in mice who were given the extract, had restored to nearly youthful levels, along with restored levels of inflammation. Blueberry extract was found to also increase the level of antioxidants in aged rats to that of young rats. In conclusion, this preliminary study has shown an effect of blueberry extract on aging biomarkers in the liver of older mice, though a further analysis should be done to find exact root causes of these positive effects.

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