
Five Numbers at Age 42 Predicted Who Reached 90, and Who Was Still Happy When They Got There
A Finnish study that followed 2,690 men until nearly all of them had died, published in late August, answers the question every healthy-habits lecture skips: do the extra years feel good?

Blood Proteins Shift Sharply at Menopause, and a New Study of Nearly 15,000 Women Links That Shift to Later Memory Decline
A Nature Medicine paper out September 22 finds the change tracks hormones more than birthdays. The link to dementia is real but modest, and there is nothing to test for yet.
Do you want to live to 120 in vibrant good health?

Turning Off Growth Hormone at Middle Age Helped Mice Live Longer, the Opposite of What Anti-Aging Clinics Sell
*A new study in Aging Cell cut growth hormone signaling in mice at the human equivalent of about age 40. Females gained 8% in median lifespan, and males maintained more strength, but the gains were smaller than in lifelong models.

Mice Lived Longer on NMN, but a Drug That Stops an Enzyme From Cutting NAD Production Did Better
A Science Advances study out September 17 traces part of the age-related drop in NAD, the molecule behind a booming supplement market, to an enzyme inside blood vessel walls. The mice were engineered to age fast, which limits what it means for you.

Bill Ackman's $400 Million Brain and Longevity Institute Just Made Its First Big Bet, and It Was a Brain Implant.
Five weeks after launch, the Ackman Oxman Institute helped lead a $250 million round for Precision Neuroscience. The mitochondria treatment that inspired it remains a single patient whose benefit faded within weeks.
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