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People over 100 years might have the cure for atherosclerosis

November 4, 2020

People over 100 years produce fifteen times more a bacterium that can reduce atherosclerosis and heart disease risk
This bacteria called E. limosum can prevent the production of TMA, which can lead to atherosclerosis
New researches are being developed to find out how these bacteria might reduce other conditions besides cardiovascular disease

Eubacterium limosum is a bacterium that can be found in adults’ digestive system; these bacteria increase their quantity over time, reaching even fifteen times more on people over 100 years. During the last decade, numerous researches have been conducted to understand how E. limosum works. As a result of this, they found that E. limosum can prevent trimethylamine production (TMA) in the body; when TMA is not adequately eliminated, TMA can cause conditions like atherosclerosis and cardiovascular disease. “Over the last decade, it has become apparent that bacteria in the human gut influence our health in many ways. The organism we studied affects health by preventing a problematic compound from becoming a worse one,” says Prof Krzycki. “It’s too soon to say whether this bacterium could have therapeutic value,” says Prof. Joseph Krzycki, one of the authors of a study published in the Journal of Biological Chemistry. In this study, they pointed out that the E. limosum might contribute to L-carnitine’s demethylation and contribute to health. L-carnitine is widely used as a dietary supplement or during exercise by athletes. L-carnitine can be converted to TMA when it is broken down by other bacterias produced on human intestines. During this process, the enzyme called MtcB produced by E. limosum can remove the methyl group produced during this reaction, which is related to cardiovascular disease; hence, you can say this enzyme is preventing these diseases. “The bacterium does this for its own benefit, but it has the downstream effect of reducing the toxicity of TMA,” says Prof. Krzycki. So far, they are not many investigations about these bacteria but is known that can prevent certain health conditions; for further studies, humans volunteers will be needed to be able to isolate the E. limosum and continue with the research.

References: https://www.medicalnewstoday.com/articles/gut-bug-may-help-prevent-heart-disease-and-promote-longevity

People over 100 years might have the cure for atherosclerosis

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