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Richard Rossi
Here Are Your 5 Biggest Longevity Stories of the Week!

Oct 14, 2026

Here Are Your 5 Biggest Longevity Stories of the Week!

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Bill Ackman's $400 Million Brain and Longevity Institute Just Made Its First Big Bet, and It Was a Brain Implant

Oct 12, 2026

Bill Ackman's $400 Million Brain and Longevity Institute Just Made Its First Big Bet, and It Was a Brain Implant

Five weeks after launch, the Ackman Oxman Institute helped lead a $250 million round for Precision Neuroscience. The mitochondria treatment that inspired it remains a single patient whose benefit faded within weeks.

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Mice Lived Longer on NMN, but a Drug That Stops an Enzyme From Cutting NAD Production Did Better

Oct 12, 2026

Mice Lived Longer on NMN, but a Drug That Stops an Enzyme From Cutting NAD Production Did Better

A Science Advances study out September 17 traces part of the age-related drop in NAD, the molecule behind a booming supplement market, to an enzyme inside blood vessel walls. The mice were engineered to age fast, which limits what it means for you.

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Turning Off Growth Hormone at Middle Age Helped Mice Live Longer, the Opposite of What Anti-Aging Clinics Sell

Oct 12, 2026

Turning Off Growth Hormone at Middle Age Helped Mice Live Longer, the Opposite of What Anti-Aging Clinics Sell

*A new study in Aging Cell cut growth hormone signaling in mice at the human equivalent of about age 40. Females gained 8% in median lifespan, and males maintained more strength, but the gains were smaller than in lifelong models.

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Blood Proteins Shift Sharply at Menopause, and a New Study of Nearly 15,000 Women Links That Shift to Later Memory Decline

Oct 12, 2026

Blood Proteins Shift Sharply at Menopause, and a New Study of Nearly 15,000 Women Links That Shift to Later Memory Decline

A Nature Medicine paper out September 22 finds the change tracks hormones more than birthdays. The link to dementia is real but modest, and there is nothing to test for yet.

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Five Numbers at Age 42 Predicted Who Reached 90, and Who Was Still Happy When They Got There

Oct 12, 2026

Five Numbers at Age 42 Predicted Who Reached 90, and Who Was Still Happy When They Got There

A Finnish study that followed 2,690 men until nearly all of them had died, published in late August, answers the question every healthy-habits lecture skips: do the extra years feel good?

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Here Are Your 5 Biggest Longevity Stories of the Week!

Oct 7, 2026

Here Are Your 5 Biggest Longevity Stories of the Week!

This is the free newsletter you subscribed to. Please enjoy!

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A 142,000-Person Trial Says the Galleri Cancer Blood Test Missed Its Main Goal. An FDA Panel Backed It Anyway.

Oct 5, 2026

A 142,000-Person Trial Says the Galleri Cancer Blood Test Missed Its Main Goal. An FDA Panel Backed It Anyway.

Two studies published September 22, and an advisory vote on September 23, give the clearest picture yet of what one blood draw can and cannot tell you about cancer.

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A Gene-Edited Pig Kidney Kept a 66-Year-Old Off Dialysis for 271 Days, Then Handed Off to a Human Organ

Oct 5, 2026

A Gene-Edited Pig Kidney Kept a 66-Year-Old Off Dialysis for 271 Days, Then Handed Off to a Human Organ

It is the first time a pig organ has carried a patient all the way to a human transplant, and formal trials for people in their 50s and 60s are now starting

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Mitochondrial DNA Mutations Can Weaken the Heart on Their Own, a New Karolinska Mouse Model Shows

Oct 5, 2026

Mitochondrial DNA Mutations Can Weaken the Heart on Their Own, a New Karolinska Mouse Model Shows

When the mutations were confined to heart muscle cells, pumping strength fell by about 25 percent by 9 months and kept sliding with age.

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Old Mice Got Stronger When Scientists Blocked the Fuel Line Behind Zombie-Cell Inflammation

Oct 5, 2026

Old Mice Got Stronger When Scientists Blocked the Fuel Line Behind Zombie-Cell Inflammation

A Nature study traced the inflammation to a mitochondrial citrate pump, and blocking it for three months delayed frailty without killing a single cell.

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Eight Different Healthy Diets All Tracked With a Slower Pace of Aging in Your Blood

Oct 5, 2026

Eight Different Healthy Diets All Tracked With a Slower Pace of Aging in Your Blood

A 7,504-person German study found that these diets barely overlapped on the plate yet pointed to the same biological pathways.

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Here Are Your 5 Biggest Longevity Stories of the Week!

Sep 30, 2026

Here Are Your 5 Biggest Longevity Stories of the Week!

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A Landmark Statin Trial in Older Adults Delivers a Split Verdict

Sep 29, 2026

A Landmark Statin Trial in Older Adults Delivers a Split Verdict

The heart benefit is real. The independent-years benefit is not

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Younger Generations Show Faster Biological Aging, and It Tracks With Rising Cancer

Sep 29, 2026

Younger Generations Show Faster Biological Aging, and It Tracks With Rising Cancer

A 154,000-person study links accelerated aging to early-onset cancer in adults under 55.

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Semaglutide Extended the Lifespan of Old Female Mice by 12 Percent

Sep 29, 2026

Semaglutide Extended the Lifespan of Old Female Mice by 12 Percent

The first lifespan study of a GLP-1 drug matched calorie restriction and beat it on memory and glucose

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Two Years of Eating Less Rewrote the Inflammation Circuits in Human Blood

Sep 29, 2026

Two Years of Eating Less Rewrote the Inflammation Circuits in Human Blood

A Yale-led analysis of the only long-term calorie-restriction trial in humans identifies the switch that quiets inflammaging

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Structured Coaching Beats Health Advice at Slowing Cognitive Decline in 11 Latin American Countries

Sep 29, 2026

Structured Coaching Beats Health Advice at Slowing Cognitive Decline in 11 Latin American Countries

The two-year LatAm-FINGERS trial delivered a 55 percent bigger cognitive gain than flexible guidance.

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Here Are Your 5 Biggest Longevity Stories of the Week!

Sep 23, 2026

Here Are Your 5 Biggest Longevity Stories of the Week!

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One Infusion of Donor Stem Cells Helped Frail Seniors Walk Farther Nine Months Later

Sep 22, 2026

One Infusion of Donor Stem Cells Helped Frail Seniors Walk Farther Nine Months Later

A randomized trial in 148 adults aged 70 to 85 found a dose-dependent gain in walking endurance, and no serious side effects were attributed to the treatment

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Doctors Took Mitochondria From Her Leg, Injected Them Into Her Eyes, and She Saw Light Again

Sep 22, 2026

Doctors Took Mitochondria From Her Leg, Injected Them Into Her Eyes, and She Saw Light Again

The first mitochondrial transplant into human eyes has now been performed, and the report describing it went up last month without peer review

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Cutting One Amino Acid Stretched Male Mouse Lifespan by 23%, Without Cutting a Single Calorie

Sep 22, 2026

Cutting One Amino Acid Stretched Male Mouse Lifespan by 23%, Without Cutting a Single Calorie

A just-published Nature Aging study isolates valine as the lever, and the benefit splits sharply by sex

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Your Body Has a Health Score Doctors Aren't Checking Yet

Sep 22, 2026

Your Body Has a Health Score Doctors Aren't Checking Yet

New research says this five-part measure predicts memory trouble years before it shows up

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A Human Has Now Been Dosed With a Cell Rejuvenation Therapy

Sep 22, 2026

A Human Has Now Been Dosed With a Cell Rejuvenation Therapy

It is a real scientific first. It is also an 18-person safety study in eye disease, with no placebo and no results expected before 2027.

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The Pooled Verdict on Knee Stem Cell Injections Just Landed

Sep 15, 2026

The Pooled Verdict on Knee Stem Cell Injections Just Landed

Twenty-four randomized trials say they do reduce pain and improve function. The same analysis says nobody can yet tell you which version to buy.

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