Nov 4, 2026
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Nov 3, 2026
Two Mount Sinai studies show APOE4 actively scars the brain's circulation, and blocking one signal reversed it in mice
Treadmill-trained mice kept their egg supply, and a drug that mimics the hormone worked even without the running
A new study follows a gradual age-clock reset in cells from donors as old as 101
Two of the three also scored better on a standard field-of-vision exam, and the trial's safety board has cleared a dose three times stronger.
A lab compound called 991 grabs the energy sensor AMPK head-on, and it worked in three very different species while failing in animals born without the switch.
Oct 28, 2026
Britain's postwar rationing gave science a natural experiment: 64,809 people with less sugar in their first 1,000 days aged measurably better
Walking, stairs, and grocery bags: 14 years of data from more than 12,000 older adults show a distinct slide years before trouble strikes
Oct 27, 2026
An hour-long operation in Osaka is the first use of the approved iPS-cell heart patch outside a trial, seven months after Japan cleared it
A trial in Chicago-area retirement communities, published September 30, tested whether walking speed matters once frailty has set in. Faster won on frailty, walking speed and daily steps.
A Science Advances study published on September 30 built a "speech age" from a few minutes of talking. People with dementia had older-sounding speech than healthy adults, and the gap tracked brain and blood measures of aging.
Oct 21, 2026
Oct 20, 2026
A new Nature Aging study found a fat-related chemical signal that marks aging cells in mice without destroying the tissue. The tool is promising for research, but scanning one square millimeter currently needs about 30 hours and has not been tried in people.
A Harvard preprint posted in September found old donor hearts looked younger in young recipients, and young hearts looked older in old ones. It could widen the donor pool, but the human evidence is thin and has not been peer reviewed.
The CHOICE trial, published September 28, is the first large randomized test of hearing aids in people who already have mild memory decline. Dementia rates were similar in both groups, while far more hearing aid users saw their memory scores return to normal.
A new analysis of 3.8 million blood immune cells from 1,828 healthy people finds immune aging is not a smooth slope. Separate immune aging clocks for men and women also beat a single shared clock.
A Nature Aging study published September 29 links the loss of cardiolipin to the odd way muscles change as we age. The team also traced the molecular switch behind one of aging muscle's strangest changes.
Oct 14, 2026
Oct 12, 2026
Five weeks after launch, the Ackman Oxman Institute helped lead a $250 million round for Precision Neuroscience. The mitochondria treatment that inspired it remains a single patient whose benefit faded within weeks.
A Science Advances study out September 17 traces part of the age-related drop in NAD, the molecule behind a booming supplement market, to an enzyme inside blood vessel walls. The mice were engineered to age fast, which limits what it means for you.
*A new study in Aging Cell cut growth hormone signaling in mice at the human equivalent of about age 40. Females gained 8% in median lifespan, and males maintained more strength, but the gains were smaller than in lifelong models.
A Nature Medicine paper out September 22 finds the change tracks hormones more than birthdays. The link to dementia is real but modest, and there is nothing to test for yet.
A Finnish study that followed 2,690 men until nearly all of them had died, published in late August, answers the question every healthy-habits lecture skips: do the extra years feel good?
Oct 7, 2026
