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Credit: https://longevity.technology/news/identification-of-age-related-protein-waves-in-blood/

Can Blood Plasma Proteins Slow Aging?

November 19, 2021

Researchers found patterns in human blood proteins that vary over the course of decades, suggesting that blood plasma proteins are partially involved in aging effects.
Understanding these proteins can lead to treatments for hypertension, dementia, and the cosmetic effects of aging.
Evidence suggests that plasma proteins might slow the aging process through blood transfusions from young donors to older recipients.

Reliable research has demonstrated some interesting properties associated with blood and aging. Researchers observed that blood transfusions from young mice to old mice could positively affect the aging process, sometimes delaying or reversing the effects of aging. Ongoing research has led to new evidence of exactly which components of blood are responsible for the positive impact. Scientists at Stanford University identified nearly 3,000 proteins in human blood plasma. The researchers took samples from over 4,000 patients aged 18 to 95. The scientists were hoping to find changes in blood composition across the lifespan. They found specific proteins that move in a predictable cycle, coming in three distinct waves in the fourth, seventh, and eighth decades of life. Understanding the role of blood proteins helps researchers figure out which proteins can successfully treat aging effects. A similar study carried out by the National Institute of Aging identified 217 plasma proteins associated with aging, together forming one protein signature. The proteins were responsible for several bodily functions, including enzyme regulation, neural propagation, inflammation, and coagulation. Biopharmaceutical companies have also investigated blood plasma-based therapies for treating Alzheimer’s disease and other dementias. It is possible that specific proteins can help the brain reduce the buildup of beta-amyloid plaques that contribute to Alzheimer’s. While blood plasma therapies have significant potential benefits, the treatment is not without risk. Blood transfusion can transfer unwanted components, such as microorganisms, from a donor to a receiver. Appropriately preparing blood for transfusion requires expensive testing and preservation. Despite this, the emergence of patterns in human blood proteins over time gives an essential clue to how blood proteins impact aging. Blood protein-based therapies are a promising step toward combating aging and age-related disease. Credit: https://longevity.technology/news/identification-of-age-related-protein-waves-in-blood/

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Can Blood Plasma Proteins Slow Aging?

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