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Credit: https://www.aftau.org/news_item/tau-study-finds-hyperbaric-oxygen-treatments-halt-aging-of-blood-cells-and-reverse-aging-process/

Hyperbaric oxygen alters the aging process

January 22, 2021

  • HBOT, Hyperbaric oxygen treatments, can halt blood cells’ aging
  • It can modify the aging process in healthy aging adults  
  • The adults’ blood cells may start growing younger as the therapy proceeds

Shamir Medical Center and the University of Tel Aviv (TAU) in Israel have researched to find the reverse implications of two aging-related biological processes in the human cells. They took the help of hyperbaric oxygen procedures. Dr. Amir Hadanny, Chief Medical Research Officer at the Shamir Medical Center and Professor Shai Efrati of the Sagol School of Neuroscience at TAU conducted research on hyperbaric oxygen treatments (HBOT). They found that oxygen, when filled in a chamber at high pressure, can reciprocate two major processes related to aging and its associated problems. According to Professor Efrati, their team has been involved in hyperbaric research and therapy for several years. This hyperbaric treatment mainly focuses on exposure to high-pressure oxygen at numerous concentrations within a pressure chamber. The work included improvement in functioning of the brain damaged by injury, stroke or age. The current study scrutinizes the impact of HBOT on healthy and independent aging adults and finds whether these therapies can slow, halt, or even revert the normal aging process at the cellular level of the human organisms. The clinical trial, performed as part of an extensive Israeli research program, approaches aging as a reversible process.  The researchers introduced 35 healthy people aged 64 or over to a sequence of 60 hyperbaric sessions for 90 days. Each of the participants had given the blood samples before, during, and at the end of the procedures. In addition, they provided their blood samples a few minutes after the completion of the series of treatments. After receiving the samples, the researchers studied and compared different blood immune cells that produce DNA.     The results showed that the hyperbaric treatments reversed the aging process in two of its prominent factors:
  • The telomere, i.e., the protective areas found at both the edges of the chromosomes, did not grow shorter as usual. In fact, it grew 20-38% longer for the various types of cells.
  • The senescent cells’ quantity in the total cell population significantly reduced in number by 11-37%, depending on the cell type. The senescent cells are those old and malfunctioning cells that stop the further cell division in our body without completely dying. These cells remain active and may damage healthy cells. 
Through this experiment, Professor Efrati regards telomeres shortening as the ‘Holy Grail’ of aging biology throughout the world. He further says that many researchers across the globe are developing environmental and pharmacological interventions. These will help in enabling telomere elongation. They could achieve it with HBOT protocol. Thus, it could prove that you can reverse the aging process at the basic cellular-molecular level. As per Dr. Haddany, this is a groundbreaking study. Until now, exercises and lifestyle modifications were tried to influence the telomere shortening. However, it has opened the doors to more observations on the cellular effects of HBOT. Moreover, it can also help to identify the implications for halting the aging process.

References: https://www.aftau.org/news_item/tau-study-finds-hyperbaric-oxygen-treatments-halt-aging-of-blood-cells-and-reverse-aging-process/

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