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(n.) Using new medical science and biohacking to slow down the aging process, repair existing damage and live a dramatically longer life in peak physical and mental health.

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Intensifying research indicates science may be able to defeat aging by 2035

May 5, 2021

Longevity research is gaining momentum as more scientists and companies probe treatments that could help treat or reverse aging.
More support is however required from the scientific community, policymakers, and the public in order to achieve anti-aging goals.
Dr. Aubrey de Grey – a leading researcher in the field – argues that the world may be able to win the race against aging by 2035.

For a long time, professionals who care for senior citizens with chronic conditions have emphasized that aging be conceptualized as an attainable and worthwhile goal. But research in the field has only picked up in the last 20 years. Scientists have made massive progress in understanding aging itself and investigating mechanisms to slow or even reverse it. Already, some experts are predicting that the battle against aging could be worn as soon as in 15 years. “I now think there is a 50% chance that we will reach longevity escape velocity by 2036. After that point (the “Methuselarity”), those who regularly receive the latest rejuvenation therapies will never suffer from age-related ill-health at any age,” said Dr. Aubrey de Grey. Dr. de Grey is a biomedical gerontologist who has been a leading voice for aging reversal and damage repair for over 20 years. He is also the founder of SENS (Strategies for Engineered Negligible Senescence) that is researching some of the hardest problems related to fixing aging damage. Work done at the SENS research lab has already yielded six antiaging companies. The organization is also playing an important role in funding research work focused on repair of mitochondrial mutations and elasticity in extracellular matrix. Dr. de Grey recently shared his thoughts on progress and challenges in a feature interview published on the Next Big Future in April 2021. He argues that more work needs to be done to realize a world that is no longer crippled by aging. Dr. de Grey proposes increased scientific debate emphasizing that aging damage repair is possible, increased policy for scientific and medical programs, and more public support. The ongoing COVID-19 pandemic is an excellent example that the scientific community is capable of achieving incredible feats. Coronavirus vaccines have been developed 10 times faster than is the norm through Operation Warp Speed in the USA and similar initiatives in countries around the world. According to Dr. de Grey, aging itself (and diseases caused by aging) have been identified as some of the risk factors for severe COVID illness. Alleviating the aging burden will be crucial to making future pandemics less deadly and also contribute to a healthier and longer-lived population. Just like it has been worthwhile to save people from COVID, it is worthwhile to save people from aging. Dr. de Grey, and countless other researchers in the field, are pushing for aging to be classified as a disease that can be prevented, treated, or even reversed. This could happen sooner rather than later if recent developments are anything to go by. The FDA approved the TAME (Targeting Aging with Metformin) Trial in 2015. This is a widespread clinical trial that aims to provide proof-of-concept that aging can be treated like any other disease. Researchers at 14 leading research institutions across the country will use metformin, an FDA-sanctioned anti diabetic drug, to probe the delayed progression of age-related chronic disease among the elderly. Increased activity in the longevity and gerontology industry could be an indication that Dr. Grey’s 2036 prediction may come true. Work at the Buck Institute is bringing together dozens of scientists who are investigating ways to end age-related diseases. Dr. David Sinclair – a biogenetic professor at Harvard and one of the leading gerontology researchers – is raising $200 million for an antiaging company he co-founded. Around the world, more than 140 companies have been formed to mitigate aging and reverse aspects of aging damage. Recent data shows numerous anti-aging products in phase 1 and phase 2 clinical trials. Most of these treatments are based on research in genomic instability, cellular senescence, and stem cell exhaustion. If these treatments succeed and are made available in clinical practice within the next 15 years, then we could get rid of the aging problem by 2035 as Dr. de Grey predicted.

References: https://www.nextbigfuture.com/2021/04/how-the-world-defeats-aging-by-2035-aubrey-de-grey-interview.htmlhttps://www.nextbigfuture.com/2021/04/how-the-world-defeats-aging-by-2035-aubrey-de-grey-interview.html

Intensifying research indicates science may be able to defeat aging by 2035

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