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Credit: https://www.newsweek.com/doctors-treat-severe-pulmonary-disease-umbilical-cord-stem-cells-1718772

Stem Cell Breakthrough Promises New Treatments for Pulmonary Disease

June 24, 2022

  • Scientists at the Medical School of Hanover successfully treated a three-year-old girl’s pulmonary arterial hypertension using stem cells.
  • Mesenchymal stem cell research is a promising field that could potentially cure hundreds of diseases.
  • The work by the researchers in Hanover marks the first step toward a viable treatment for pulmonary arterial disease.
Scientists at the Medical School of Hanover, one of Germany’s top medical research facilities, have successfully treated a disease using stem cell products. The patient, a victim of a severe pulmonary condition, was a young three-year-old girl. She is diagnosed with pulmonary arterial hypertension (PAH), a condition defined by high blood pressure in the vessels that bring blood to the lungs. PAH is currently untreatable and impacts all ages. A family history of high blood pressure, previous diagnoses of clotting disorders, mitral valve disorders, and sleep apnea are all significant risk factors for PAH. Researchers treated the young patient over the course of half a year. Over that time, she received five doses of mesenchymal stem cell products. Mesenchymal stem cells, produced in bone marrow, are used by the body to repair the body’s tissue. The director of the Translational Cardiopulmonary Biomedicine research group at the Medical School of Hanover, Professor Georg Hansmann, reported that the treatment “led to a significant improvement in growth, exercise tolerance, and clinical cardiovascular variables.” An absence of adverse side effects further bolstered the researchers’ results. While acknowledging that much more research is required, Dr. Hansmann was optimistic that treatment with mesenchymal stem cells might be a viable option for patients diagnosed with PAH. Additional research into stem cells at the Medical School of Hanover also shows other benefits. The stem cells have a demonstrated effect of reducing damage in the body and slowing inflammation.  Hansmann has developed his stem cell therapy since 2011. Since then, dozens of scientists and researchers have joined him in finding ways to help patients with stem cells. Treatment with mesenchymal stem cells has few side effects, but the treatment is not perfect. Doctors must administer the therapy several times to be effective, and the results can vary from patient to patient. Nevertheless, mesenchymal stem cell research remains a promising, potent area of research that will grow considerably in the future. Credit: https://www.newsweek.com/doctors-treat-severe-pulmonary-disease-umbilical-cord-stem-cells-1718772 

References: https://www.newsweek.com/doctors-treat-severe-pulmonary-disease-umbilical-cord-stem-cells-1718772

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