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Credit: https://longevity.technology/news/ageotype-four-new-types-of-biomarker/

The Ageotype is a Revolutionary New Tool to Measure Age

January 18, 2020

  • Scientists have found a new way to characterize aging, called an “ageotype.”
  •  Ageotypes examine which parts of the body are aging the quickest.
  • Doctors may one day use a patient’s ageotype to recommend lifestyle changes or guide medical treatment.
Human age is often considered only in terms of years, and different people have different aging experiences. It can be challenging to understand why two people, both 65 years old, can experience such radically different impacts from age-related disorders. Often, lifestyle and environmental factors are to blame—for example, those who smoke cigarettes age quicker than those who do not. Recently, scientists have given more attention to genetic factors related to aging. Researchers are actively investigating biomarkers and metabolic aging processes to understand how humans age differently on a cellular level. Research conducted by Michael Snyder, Ph.D., a geneticist at the Stanford University School of Medicine, investigated the link between the molecular makeup of a participant’s cells and their overall health. The scientists measured the molecular chemistry of the research participants, aged 29 to 75, over the course of two years. From this study, the researchers identified four distinct “ageotypes,” or parts of the body where aging was most active. Different bodily systems can age at different rates. Dr. Snyder’s team found that their study participants tended to age most in the kidney, liver, and immune system. Scientists also identified participants whose cellular metabolism aged faster than other body systems. According to Dr. Snyder, identifying which bodily systems experience the most significant age-related effects could “help individuals zero in on health risk factors and find areas in which they’re most likely to encounter problems.” Early research suggests that using molecular biomarkers to develop personalized lifestyle improvements based on ageotype could significantly slow a person’s aging. Other age-related research has demonstrated similar promise, with a recent study finding a positive correlation with a specific molecular makeup in those aged over 100.  Credit: https://longevity.technology/news/ageotype-four-new-types-of-biomarker/ 

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