Scientists Link Epigenetic Age Acceleration to Mortality
By using four popular methylation clocks, scientists have established that epigenetic age acceleration (EAA) is linked to aging and mortality in human beings. The researchers analyzed data from the Women’s Health Initiative—an important population study with a sample size of 1813 women. Unfortunately, this was also one of the limitations of the study because on
Can blueberry extract reduce aging biomarkers?
Published in Oxidative Medicine and Cellular Longevity, a recent study has shown that blueberry extract can improve age-related biomarkers in livers of aging male rats. Researchers point out that blueberries are rich in anthocyanins, which have been reportedly shown to have positive effects in past studies. Additionally, they note that there hasn’t been a study
The Shrew's Two-Year Lifespan Might Hold the Key to Human Longevity
Gene regulation and expression could hold the keys to slowing aging, according to new research from the University of Rochester. Researchers at the university discovered two critical gene expression regulation mechanisms that contribute heavily to longevity. Scientists built a genetic profile of long-lived and short-lived rodents by studying various rodent species. Shrews, for example, have
Breakthrough in Ovarian Aging: Study Shows Promising Results
Scientists have documented that resveratrol reverses several features of ovarian aging in mice while improving mitochondrial health and activating major sirtuins. In most mammals, ovarian aging is accelerated compared to other organs and systems. While the reasons for this accelerated loss are not clear, some notable triggers include issues with ATP production, a decrease in
The 2022 Rejuvenation Startup Summit: A Complete Success
Berlin recently concluded the Rejuvenation Startup Summit that took place between the 14th and 15th of October 2022. The summit had more than 400 participants from over 30 countries, and was focused on showcasing the research and developments in rejuvenation biotech. This vibrant networking event also brought together international members of the longevity capital/investor ecosystem
Stem Cell Breakthrough Promises New Treatments for Pulmonary Disease
Scientists at the Medical School of Hanover successfully treated a three-year-old girl’s pulmonary arterial hypertension using stem cells. Mesenchymal stem cell research is a promising field that could potentially cure hundreds of diseases. The work by the researchers in Hanover marks the first step toward a viable treatment for pulmonary arterial disease. Scientists at the
A Newly Discovered Genetic Factor May Impact Sperm Count
Researchers at the Pennsylvania School of Veterinary Medicine identified a new genetic sequence called DOT1L as a factor in sperm production. Spermatogonial stem cells lacking this gene factor could not produce healthy sperm. Identifying the genetic pathway of DOT1L opens up new avenues for research into male infertility. Spermatogonial stem cells are necessary to produce
New Study Knocks Three Years Off Participant's Biological Age
New research from the Helfgott Research Institute, in conjunction with the Yale University Center for Genome Analysis, has demonstrated that changes in diet and lifestyle can successfully roll back biological aging in humans. Most people are familiar with chronological age, or a person’s age in years. Biological age refers to more subtle and complex factors
Saliva Test for Biological Age Has High Accuracy
Endurance RP, a subsidiary of Deep Longevity, Inc, has created a saliva test that accurately measures biological age. The Endurance researchers based their work on pre-existing tests which have been proven to examine blood-based biomarkers, specifically DNAm aging clocks. A separate division of Deep Longevity previously released DeepMAge, a test that measures DNA modification to
Baylor Scientists Shine New Light on Optogenetics Research
The human gut microbiome is full of bacteria, fungi, protozoa, and other unicellular organisms. Evidence suggests that the health of the human gut biome plays a significant role in regulating aging. Researchers have found it challenging to isolate specific microbial species to determine how they influence the gut biome. New breakthroughs from the Baylor College